Published
2026-09-04
Section
Articles
How to Cite
高海拔环境寻常痤疮的流行病学特征及临床干预策略
张 红燕
西藏大学医学院
陈 欣煜
西藏大学医学院
杨 洪浩
西藏大学医学院
孙 成琼
西藏大学医学院
DOI: https://doi.org/10.59429/zxyy.v3i4.15133
Keywords: 高原环境；寻常痤疮；皮肤屏障；光防护
Abstract
目的：梳理高原地区寻常痤疮的临床特征，探讨高海拔环境对痤疮发病机制及皮肤屏障功能的影响，为临床 防治提供理论依据。方法：采用文献回顾法，对国内外相关研究进行归纳分析。结果：与平原地区相比，高原痤疮 在移居人群中发病率高、皮损进展快且炎性损害严重。临床常表现为炎性丘疹、脓疱或结节，并伴有皮肤屏障受损 和炎症后色素沉着（PIH）。机制上，高海拔环境（海拔 >2500m）下强紫外线、高寒干燥与低氧暴露可协同诱导脂 质过氧化、角质层屏障破坏、微生态失衡及炎症的加剧。结论：高原痤疮具有独特的临床表型与病理生理特征，临 床治疗须以抗炎为基础，并强化皮肤屏障修复与全程光防护。
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