Intelligent patrol and targeted therapy integrated breast cancer defense nanorobot: Technology, application, and prospects
Haidi Yu
Hebei Oriental University
DOI: https://doi.org/10.59429/esta.v13i1.13396
Keywords: breast cancer; nanorobot; intelligent patrol; targeted therapy; biosensor; CRISPR; FRET
Abstract
Breast cancer, with the highest morbidity and mortality among women globally, presents significant challenges in early diagnosis and precision treatment. This paper proposes a breast cancer defense nanorobot integrating intelligent patrol and targeted therapy functions. The nanorobot incorporates biosensors, targeting technology, drug delivery systems, and intelligent navigation control, enabling highly sensitive identification, precise localization, and controlled drug release. Structurally, it utilizes DNA origami and biodegradable materials for biocompatibility and stability. Functionally, it combines FRET sensing with CRISPR gene editing to enhance diagnostic accuracy and therapeutic efficacy. Through multidisciplinary collaboration, the system underwent full-chain development from design to experimental validation. Results demonstrate excellent motility, targeting ability, and therapeutic effect, showing broad application prospects in breast cancer treatment.
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