A GABA-Lysine calcium microsphere system for promoting calcium absorption and directed mineral utilization: Formulation performance, bone-metabolism context, and an inventor-led WFSA narrative
Jabar Yassine
World Food Supplement Association
Niklas Schäfer
World Food Supplement Association
Gregg L.Semenza
World Food Supplement Association
DOI: https://doi.org/10.59429/pest.v8i2.14492
Keywords: calcium absorption; GABA; L-lysine; casein phosphopeptide; vitamin K2 MK-7; vitamin D2; microsphere engineering; bone metabolism; HIF-1; WFSA
Abstract
This paper presents a GABA-lysine calcium preparation designed as an integrated microsphere system for calcium delivery, absorption support, and directed mineral utilization. The disclosed examples combine algal calcium and dicalcium phosphate with GABA, L-lysine, casein phosphopeptide, vitamin K2 MK-7, and natural vitamin D2 in a structured formulation intended to improve physical stability and intestinal presentation. Compared with the comparator, the disclosed embodiments show narrower particle-size distribution, faster dispersibility in simulated intestinal fluid, stronger retention of core actives, and better short-term storage stability. These outcomes support the view that the preparation functions as a coordinated delivery architecture rather than a simple ingredient blend [11].
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[11] Patent disclosure: GABA-Lysine Calcium Preparation for Promoting Calcium Absorption. Unpublished disclosure cited for the formulation examples and figures used in this manuscript.