Published
2025-01-14
Section
Articles
How to Cite
神经退行性疾病眼球运动的研究进展
刘 述廷
大连市友谊医院神经内科
张 平平
大连市妇女儿童医疗中心（集团）
DOI: https://doi.org/10.59429/xjjz.v6i4.8633
Keywords: 神经退行性疾病；阿尔茨海默病；帕金森病；眼球运动；扫视
Abstract
人类是视觉主导的物种，我们感知什么取决于我们看哪里。参与眼球运动的神经通路和大脑区域包括大脑、 脑干和小脑，眼球运动对我们与环境的相互作用至关重要。因此，异常的眼球运动可提示存在神经退行性变，实验 结果表明眼球运动在神经退行性疾病（neurodegenerative diseases，ND）中受到影响。这可能是 ND 中一些认知和运 动障碍的原因。在一些患者中，眼球运动的体征是诊断的关键。因此，对神经退行性疾病患者的眼动进行仔细的临 床检查是神经和认知评估的宝贵辅助手段。眼动检查通常对诊断不是必需的，但可以作为临床检查的有效补充。我 们的目的是确定眼球运动的改变是否可以告诉我们 ND 的进展，如阿尔茨海默病（Alzheimer’s，AD）、多系统萎缩 （multiple system atrophy,MSA）、帕金森病（Parkinson’sdiseases，PD）和其他 ND。探索眼球运动的类型、神经退 行性疾病眼球运动异常形式及其临床意义，我们能够发现与 ND 症状相关的显著眼球运动变化，这使我们能够深入 了解 ND 的机制，以期为临床预测疾病进展和鉴别诊断提供新的潜在标志物。
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