ISSN
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Vol 1 No 1 (2024)
Published November 5, 2024
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Table of Contents
Open AccessArticles
by Jannatul FerdousNazia, Abu BakarSiddik, Md. Al-AminHossen, Adiatuj JahanRimu, Tasnim Shamrin, Sadia Islam, Hazera AkterMukta, Md. AshiqurRahman
2024,1(1);
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Abstract
Background: The study aims to identify bacterial isolates and drug susceptibility patterns from patients with pus and wound discharge, addressing the issue of antibiotic resistance and the need for rational use in controlling infections. Methods and Materials: The cross sectional study at Bangladesh University of Health Sciences involved purposive sampling and Pus & tracheal aspirates from patients. It followed standard laboratory procedures for bacterial species identification and antimicrobial susceptibility testing using disk diffusion method following CLSI guidelines 2017. Results: This study examined 400 samples over a year, with most being pus (84%) and tracheal aspirate (16%). Males were predominant (56%), and gram-negative bacteria were predominant (74%). Staphylococcus aureus was the most sensitive to tigecycline (83%), followed by Meropenem & Doxycycline (67%), Gentamicin (58%), Cotrimoxaxole, Chloramphenicol & Colistin (42% each). Klebsiella pneumoniae were 100% sensitive to Meropenem, Ciprofloxacin & Tigecycline, and were 100% resistant to Cefotaxime, Cefixime & Cotrimoxazole. Escherichia coli were highly sensitive to Meropenem & Tigecycline, followed by Ceftazidime (69%), Gentamicin (63%), Ciprofloxacin & Colistin (62%), Doxycycline, Cefotoxime, Cefoxitin, Cotrimoxazole & Chloramphenicol (50%), Cefixime (31%), Amoxycillin (25%), and Ampicillin (24%). Staphylococcus aureus were most resistant to Vancomycin & Linezolid (75%). Multidrug resistance was found in 320 (80%) organisms in pus & tracheal aspirate. Conclusion: Multiple organisms were isolated from tracheal aspirate and pus, with most being multidrug resistant. The appropriate antibiotic for treatment should be chosen based on culture sensitivity.
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